Don't expect Makoto to go down without a fight, as she can and will fight back with full force and energy. If she can be taken down, her loose clothing makes her difficult to bind with ropes, so stick with tape or belts on a first-time basis. Her muscular body makes it difficult to pinpoint a particular weak spot, but it's actually hidden in plain sight since she really shivers nicely when touched at the base of her neck. She tends to yell, so use a heavy gag. If that's unavailable, something that highlights her sharp eyes works nicely.